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Scientists warn of 'super variants' of nCoV 9
Every week, a group of epidemiological experts in the Northeast United States participates in an online meeting to discuss nCoV variants in the world.
Since it first appeared in India in December 2020, Delta has become so popular that scientists think the virus has stopped mutating and entered a stable state.
Some new variants continue to appear, such as AY.4.2 or Delta Plus recently, which are 10-15% more transmissible.
`There are quite a few types of Delta Plus. In a recent interview, I identified Delta Plus as the name for all the variants of concern right now. But it is not much more transmissible than Delta,` Hanage said.
Hanage and his colleagues still review the Covid-19 database every week, the purpose of the meeting is to predict what happens next.
One theory is that after the initial big change, creating Alpha and Delta, nCoV is now mutating slowly and steadily, eventually going beyond the control of current vaccines.
Francois Balloux, Director of the UCL Institute of Genetics, said: `This type of evolution is called ‘antigenic drift’, when viruses evolve to escape the immune system, often causing small to medium epidemics.
Another scenario is that nCoV will mutate into a completely new strain, with a completely different level of transmission, virulence and ability to evade immunity.
`Right now the pandemic is mainly due to Delta. The super variant I’m talking about is more powerful than Delta Plus. I don’t think Delta Plus is worrying and can grow strongly in other countries. But the sustainable variant
The image shows healthy cells (red) being invaded by nCoV (yellow).
Supervariation arises in a variety of ways.
In the second half of 2020, epidemiological experts observed the phenomenon of viral recombination. In it, different versions of nCoV exchange mutations and combine to form completely new strains.
Fortunately, this phenomenon is not common, says Mr. Gupta.
`Delta is currently the dominant strain, so the rate of new variants appearing is less. But in some areas, we cannot take samples for testing, nor do we know what the epidemic situation is. So, the scenario is
nCoV can also have a series of major mutations, creating a strongly upgraded Delta version or a completely different virus strain.
Many people are concerned that antiviral drugs can promote nCoV to evolve to adapt to the human body.
Super variants are also at risk of appearing in countries with persistently high infection rates such as the UK.
`The more infections each day, the more likely it is that a patient
Earlier this year, Professor Gupta published a study showing that this condition can occur in seriously ill patients who have been given convalescent plasma containing antibodies to kill nCoV.
Scientists try to model the new nCoV super variant.
This is the result of natural selection.
While this may sound scary, it’s not all bad news.